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CD1B, Recombinant, Human, aa18-303, His-Tag (T-cell Surface Glycoprotein CD1b, CD1, CD1A, R1)

Cat no: 138619

CD1B, Recombinant, Human, aa18-303, His-Tag (T-cell Surface Glycoprotein CD1b, CD1, CD1A, R1)

CD1B is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. This protein contains 1 Ig-like (immunoglobulin-like) domain. CD1B is antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. \n\nSource:\nRecombinant protein corresponding to aa18-303 from human CD1B at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~34.2kD (310aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMSEHAFQ GPTSFHVIQT SSFTNSTWAQ TQGSGWLDDL QIHGWDSDSG TAIFLKPWSK GNFSDKEVAE LEEIFRVYIF GFAREVQDFA GDFQMKYPFE IQGIAGCELH SGGAIVSFLR GALGGLDFLS VKNASCVPSP EGGSRAQKFC ALIIQYQGIM ETVRILLYET CPRYLLGVLN AGKADLQRQV KPEAWLSSGP SPGPGRLQLV CHVSGFYPKP VWVMWMRGEQ EQQGTQLGDI LPNANWTWYL RATLDVADGE AAGLSCRVKH SSLEGQDIIL YWRNPTSIGS\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138619

Size

20ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.2M sodium chloride, 1mM DTT, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Shamshiev A., et al. (2000) Immunity 13:255-264 2. Winau F., et al. (2004) Nat. Immunol. 5:169-174.

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