Home  >  Products  >  CD2 (Erythrocyte Receptor, FLJ46032, LFA-2, LFA-3 Receptor, Rosette Receptor, SRBC, T11, T-Cell Surface Antigen CD2, T-Cell Surface Antigen T11/Leu-5)

CD2 (Erythrocyte Receptor, FLJ46032, LFA-2, LFA-3 Receptor, Rosette Receptor, SRBC, T11, T-Cell Surface Antigen CD2, T-Cell Surface Antigen T11/Leu-5)

Cat no: C2253-01T


Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Human CD2 is a T-lineage glycoprotein with roles in cell-cell adhesion and the transduction of activation signals. Multiple ligands for CD2 include CD58 (LFA-3), CD59, and CD48. CD2 may play a role in regulating T cell anergy. Applications: Suitable for use in Western Blot and Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 5x10e5 cultured HPB-MLT human tumor cells were washed and incubated 45 min on ice with 80ul anti-CD2 antibody at 1ug/ml. Cells were washed twice and incubated with Goat anti-Mouse IgG/FITC after which they were washed three times, fixed and analyzed by FACS. Cells stained positive with a mean shift of 1.12 log10 fluorescent units when compared to a Mouse IgG2a negative control at a similar concentration. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2253-01T
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Western Blot
Size: 100ug
Form: Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100,mM potassium chloride, 150mM sodium chloride.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by Protein A affinity chromatography.
References: 1. K.F. Kozarsky, et al, (1993) Cell Immunol 150: 235-246. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 342-352. 2. G.M. Bell & J.B. Imboden (1995) J Immunol 155: 2805-2807.
Additional info: Recognizes human CD2. Recognizes the T111 epitope of the 50kD human CD2 molecule. Useful for studying CD2 ligand-binding mechanisms involved with T cell development and activation.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*

Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave