Home  >  Products  >  CD20 (B-lymphocyte Antigen CD20, B-lymphocyte Surface Antigen B1, Bp35, Leukocyte Surface Antigen Leu-16, Membrane-spanning 4-domains Subfamily A Member 1, MS4A1)
CD20 (B-lymphocyte Antigen CD20, B-lymphocyte Surface Antigen B1, Bp35, Leukocyte Surface Antigen Leu-16, Membrane-spanning 4-domains Subfamily A Member 1, MS4A1)

CD20 (B-lymphocyte Antigen CD20, B-lymphocyte Surface Antigen B1, Bp35, Leukocyte Surface Antigen Leu-16, Membrane-spanning 4-domains Subfamily A Member 1, MS4A1)

Cat no: C2270-08D

Supplier: United States Biological
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CD20 is expressed on pre-B cells, resting, activated and neoplastic B cells but is absent from pro-B cells, plasma cells or mycioma cells. It is also expressed on some non T-ALL cells and possibly on follicular dendritic cells but not on monocytes, macrophages, neutrophils, red blood cells or platelets. In normal lymph nodes and tonsils, CD20 is detected on B cells in germinal centers while lower density expression is seen on cells in the mantle zone. CD20 is associated with transmembrane Ca+2 transport and is involved in the regulation of B cell proliferation and differentiation. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.003-0.01ug/ml Immunohistochemistry (paraffin): 2-5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Daudi lysate and Human Spleen Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2270-08D
Reactivities: Human
Hosts: Goat
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Stamenkovic I, Seed B. Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein. J Exp Med 1988 Jun 1;167(6):1975-80 PMID: 3260267.
Additional info: Recognizes human CD20.

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