CD22 (HIB22) Antibody

Cat no: 251067

Supplier: ABBIOTEC

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Description
Additional Information

The CD22 (HIB22) antibody recognizes a 130-140 kDa type-I transmembrane glycoprotein that is a B cell restricted antigen. CD22 antigen is e, Xenopus/Amphibian,pressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B lymphocytes. CD22 e, Xenopus/Amphibian,pression is increased after activation and lost at the terminal stage of B cell differentiation. Most B cell leukemias and lymphomas also e, Xenopus/Amphibian,press CD22. It is not e, Xenopus/Amphibian,pressed in T cells,Mouse,onocytes and granulocytes. CD22 is an early marker for B-ALL and hairy-cell leukemia diagnostic. CD22 is an adhesion molecule that amplifies the signal of B cell activation. CD22 ligands are CD45RO antigen on T cells and CD75 antigen on B cells participating in the homotopic interaction of T and B cells.

Catalogue number:	251067
Reactivities:	Human
Applications:	Flow Cytometry
Size:	2 ml
Accession:	P20273, NP_001762
Format:	Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody,PorcineE-conjugated Antibody
Isotype:	mouse IgG1
Clonality:	HIB22
Additional info:	B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2; Siglec-2; Leu-14; B-lymphocyte cell adhesion molecule; BL-CAM; CD22; SIGLEC2