CD226, Recombinant, Human, aa19-254, His-Tag (CD226 Antigen, DNAM-1, DNAM1, PTA1, TLiSA1)

CD226 is a 65kD glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. This protein also plays a role in megakaryocytic cell maturation. \n\nSource:\nRecombinant protein corresponding to aa19-254 from human CD226 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~29.4kD (259aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSEEVLWHT SVPFAENMSL ECVYPSMGIL TQVEWFKIGT QQDSIAIFSP THGMVIRKPY AERVYFLNST MASNNMTLFF RNASEDDVGY YSCSLYTYPQ GTWQKVIQVV QSDSFEAAVP SNSHIVSEPG KNVTLTCQPQ MTWPVQAVRW EKIQPRQIDL\nLTYCNLVHGR NFTSKFPRQI VSNCSHGRWS VIVIPDVTVS DSGLYRCYLQ ASAGENETFV MRLTVAEGKT DNQYTLFVA\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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