CD235ab (HIR2) Antibody

Cat no: 250984

Supplier: ABBIOTEC

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Description
Additional Information

The CD235ab (HIR2) antibody recognizes a N-terminal homologous portion of glycophorin-A (GPA) and glycophorin-B (GPB), which are single-pass membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities while GPB accounts for S, s and U specificities. GPA and GPB provide the cells with a large mucin-like surface acting as a barrier to cell fusion, therefore minimizing aggregation between red blood cells in the circulation. The CD235ab (HIR2) antibody agglutinates untreated RBC but failed to agglutinate papain-treated cells. This antibody primarly binds to GPA and weakly to GPB. CD235ab is e, Xenopus/Amphibian,pressed on early erythroblasts, late erythroblasts, erythroblasts,Mouse,ature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells. Mature erythrocytes are CD235ab positive whereas CD45 and CD71 negative.

Catalogue number:	250984
Reactivities:	Human
Applications:	Flow Cytometry, Immunohistochemistry
Size:	0.1 mg
Accession:	P02724; P06028
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG2b
Clonality:	HIR2
Additional info:	CD235ab; CD235a; Glycophorin-A; PAS-2; Sialoglycoprotein alpha; MN sialoglycoprotein; GYPA; GPA; CD235B; Glycophorin-B; PAS-3; Sialoglycoprotein delta; SS-active sialoglycoprotein; GYPB; GPB