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CD235ab (HIR2) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251096

CD235ab (HIR2) Antibody

The CD235ab (HIR2) antibody recognizes a N-terminal homologous portion of glycophorin-A (GPA) and glycophorin-B (GPB), which are single-pass membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities while GPB accounts for S, s and U specificities. GPA and GPB provide the cells with a large mucin-like surface acting as a barrier to cell fusion, therefore minimizing aggregation between red blood cells in the circulation. The CD235ab (HIR2) antibody agglutinates untreated RBC but failed to agglutinate papain-treated cells. This antibody primarly binds to GPA and weakly to GPB. CD235ab is e, Xenopus/Amphibian,pressed on early erythroblasts, late erythroblasts, erythroblasts,Mouse,ature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells. Mature erythrocytes are CD235ab positive whereas CD45 and CD71 negative.

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SPECIFICATIONS

Catalog Number

251096

Size

2 ml

Applications

FC

Reactivities

Hum

Format

Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody,PorcineE-conjugated Antibody

Isotype

mouse IgG2b

Accession

P02724; P06028

Clonality

HIR2

Additional Info

CD235ab; CD235a; Glycophorin-A; PAS-2; Sialoglycoprotein alpha; MN sialoglycoprotein; GYPA; GPA; CD235B; Glycophorin-B; PAS-3; Sialoglycoprotein delta; SS-active sialoglycoprotein; GYPB; GPB

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