CD24 (L14) pAb

CD24 is a GPI-linked membrane sialoglycoprotein that is expressed on pro-B,pre-B and mature B cells, and its expression is decreased after B cell activation.CD24 is also found on granulocytes and a small fraction of thymocytes and neuroblastomas, but not on plasma cells. CD24 may play a role in the regulation of B cell proliferation and differentiation. CD24 is expressed in hematological malignancies as well as in a large variety of solid tumors. A shift from apical localization to cytoplasmic staining of CD24 is a surrogate marker of stromal invasion in ovarian serous tumors of borderline malignancy. CD24 protein can be a B cell differentiation marker that is expressed on mature resting B cells and disappears upon stimulation.

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SPECIFICATIONS

Catalog Number

BS9005

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to the N-terminal of Human CD24.

Species

CD24 (L14) pAb detects endogenous levels of CD24 protein.

Dilutions

WB:500~1000

Swiss Prot

P25063

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul