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CD24 (Signal Transducer CD24, Small Cell Lung Carcinoma Cluster 4 Antigen, CD24A)

CD24 (Signal Transducer CD24, Small Cell Lung Carcinoma Cluster 4 Antigen, CD24A)

Cat no: C2275-06F

Supplier: United States Biological
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CD24 is a 35-45 kD glycosylphosphatidylinositol (GPI)-linked protein also known as heat stable antigen (HSA), BA-1, Ly-52, and nectadrin. It is expressed on the surface of B cells (but not plasma cells), granulocytes, follicular dendritic cells, and epithelial cells. CD24 may play a role in the regulation of B-cell proliferation and maturation. CD24 crosslinking induces a Ca2+ flux in mature B cells. CD24 has been shown to interact with CD62P (P-selectin). Applications: Suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2275-06F
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Schlossman, S., et al. Eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. 2. McMichael, A., et al. 1987. Leucocyte Typing III. Oxford University Press. New York. 3. Yang , G. P., et al. 1999. Nucleic Acids Research 27:1517. 4. Kristiansen, G., et al. 2003. Clin. Cancer Res. 9:4906. 5. Schlossman, S., et al. Eds. 1995. Leukocyte Typing V. Oxford University Press. New York.
Additional info: Recognizes human CD24. Species Crossreactivity: chimpanzee.

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