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CD25 (Interleukin-2 Receptor Subunit alpha, IL-2 Receptor Subunit alpha, IL-2-RA, IL-2R Subunit alpha, IL2-RA, TAC Antigen, p55, IL2RA)

CD25 (Interleukin-2 Receptor Subunit alpha, IL-2 Receptor Subunit alpha, IL-2-RA, IL-2R Subunit alpha, IL2-RA, TAC Antigen, p55, IL2RA)

Cat no: C2276-10K

Supplier: United States Biological
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CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor a chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor b(CD122) and common g chains (CD132) to form the high affinity IL-2R complex. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2276-10K
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Schlossman, S., et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. 2. Kmieciak, M., et al. 2009. J. Transl. Med. 7:89. (FC) 3. Taniguchi, T., et al. 1993. Cell 73:5. 4. Waldmann, T. 1991. J. Biol. Chem. 266:2681.
Additional info: Recognizes human CD25. Species Crossreactivity: cynomolgus, rhesus.

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