Home  >  Products  >  CD27 (CD27 Antigen, CD27L Receptor, T-cell Activation Antigen CD27, T14, Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7) (Biotin)
CD27 (CD27 Antigen, CD27L Receptor, T-cell Activation Antigen CD27, T14, Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7) (Biotin)

CD27 (CD27 Antigen, CD27L Receptor, T-cell Activation Antigen CD27, T14, Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7) (Biotin)

Cat no: C2379-10M

Supplier: United States Biological
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CD27 is a 50-55kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells and NK cells. CD27 binds to CD70, and plays an important role in costimulation of T cell activation and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-kB and SAPK/JNK activation. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.5ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2379-10M
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Conjugates: Biotin
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Knapp, W., et al., Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
Additional info: Recognizes human CD27.

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