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CD274, Low Endotoxin (B7-h1 Protein, B7-H1, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1)

Cat no: C2549-22B

Supplier: United States Biological

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CD274, also known as B7-H1 and PD-1L, a cell surface glycoprotein which is a member of the B7 family of co-stimulatory molecules. CD274 is expressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells, endothelial cells and epithelial cells in response to Interferons alpha, beta and gamma. CD274 is reported to possess dual functions; inhibition of activated effector T cells and co-stimulation of na

Catalogue number:	C2549-22B
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size:	500ug
Form:	Supplied as a liquid in PBS. No preservative added.
P type:	Mab
Isotype:	IgG2a
Purity:	Purified by Protein G Chromatography. Endotoxin: (same/less than) 0.01EU/ug.
Alternative names:	PD-L1
References:	1. Kanai, T. et al. (2003) Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. J. Immunol. 171: 4156-4163. 2. Yamazaki, T. et al. (2002) Expression of programmed death 1 ligands by murine T cells and APC. J. Immunol. 169: 5538-5545.
Additional info:	Recognizes mouse CD274

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CD274, Low Endotoxin (B7-h1 Protein, B7-H1, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1)

Cat no: C2549-22B

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