Home  >  Products  >  CD28 (MGC138290, T cell Antigen CD28, T cell Specific Surface Glycoprotein, CD28, Tp44)
CD28 (MGC138290, T cell Antigen CD28, T cell Specific Surface Glycoprotein, CD28, Tp44)

CD28 (MGC138290, T cell Antigen CD28, T cell Specific Surface Glycoprotein, CD28, Tp44)

Cat no: C2380-02C

Supplier: United States Biological
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CD28 is a 44kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. This antibody blocks the binding of 37.51 antibody to CD28 and costimulates T cell activation and proliferation. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)1ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2380-02C
Reactivities: Mouse
Hosts: Mouse
Applications: Flow Cytometry
Size: 500ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Lenschow DJ, et al. 1996. Annu. Rev. Immunol. 14:233. 3. Gross JA, et al. 1992. J. Immunol. 149:380.
Additional info: Recognizes mouse CD28.

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