CD28 (T-cell-specific Surface Glycoprotein CD28)

Cat no: C2380-02B

Supplier: United States Biological

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CD28 is a 44kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. This antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)1ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C2380-02B
Reactivities:	Mouse
Applications:	Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size:	50ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type:	Mab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
References:	1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Lenschow DJ, et al. 1996. Annu. Rev. Immunol. 14:233. 3. Gross JA, et al. 1992. J. Immunol. 149:380.
Additional info:	Recognizes mouse CD28.

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CD28 (T-cell-specific Surface Glycoprotein CD28)

Cat no: C2380-02B

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