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CD284 Polyclonal Antibody

Cat no: ABP50903

CD284 Polyclonal Antibody

The protein(toll like receptor 4)encoded by TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in TLR4 have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for TLR4.

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SPECIFICATIONS

Catalog Number

ABP50903

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Gene Id

7099

Isotype

Rabbit IgG

Accession

O00206

Clonality

Polyclonal

Concentration

1 mg/ml

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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