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CD3

Cat no: C2253-38E


Supplier: United States Biological
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The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intracytoplasmic; however, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells and is present in majority of T cell neoplasms. CD3 antigen is expressed on approximately 60
Catalogue number: C2253-38E
Reactivities: Human, Mouse, Bovine, Canine, Chicken/Bird, Feline, Non-Human Primate, Porcine
Hosts: Rat
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Size: 200ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes a highly conserved epitope of the human CD3 molecule expressed by T lymphocytes. Species Crossreactivity: bovine, canine, equine, Rhesus Monkey, porcine, chicken, mouse, duck, koala, Harbor Porpoise, Alpaca, Cynomolgus Monkey, Spotted Hyena, sea lion, feline, Amazon Parrot and raccoon

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