The T-cell receptor-CD3 complex (CD3-TCR) plays an important role in mediating signaling transduction. The CD3-TCR complex consists of either a TCR alpha/beta or TCR gamma/delta heterodimer co-expressed at the cell surface with the CD3 subunits: CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These subunits are single-pass type I membrane proteins expressed on normal peripheral blood lymphocytes, thymocytes and Purkinje cells in the cerebellum.
Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (Frozen): 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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