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Products CD3 (Early T Cell Marker, T Cell receptor Complex, TCR) (FITC)
| Catalogue number: | C2253-38B3 |
| Reactivities: | Rat |
| Hosts: | Mouse |
| Applications: | Flow Cytometry |
| Size: | 50ug |
| Form: | Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC). |
| P type: | Mab |
| Isotype: | IgM |
| Purity: | Purified |
| References: | 1. Tanaka, T.et al. (1989) Characterization of a CD3-like rat T cell surface antigen recognised by a monoclonal antibody. J. Immunol. 142: 2791-2795.2. Nicolls, M.G. et al. (1992) Induction of long-term specific tolerance to allografts in rats by therapy with an anti-CD3-like monoclonal antibody. Transplantation 55: 459-468. 3. McKechnie, N. M. et al. (1997) Immunization with the cross-reactive antigens Ov39 from Onchocerca volvulus and hr44 from human retinal tissue induces ocular pathology and activates retinal microglia J. Infectious Disease. 176: 1334-43. |
| Additional info: | Recognizes rat CD3, a 25kD antigen which is found on rat T-cells. Does not react with rat B cells. Functionally the addition of the antibody to a culture of rat T cells induces the proliferation of T-cells in the presence of PMA(2). |
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