CD3 (HIT3a) Antibody

Cat no: 251046

Supplier: ABBIOTEC

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Description
Additional Information

The CD3 (HIT3a) antibody recognizes the 17-19 kD ?-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) comple, Xenopus/Amphibian,. The CD3 antigen is e, Xenopus/Amphibian,pressed in the cell cytoplasm during the early stage of T cell development and is e, Xenopus/Amphibian,pressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. The clone HIT3a has a strong mitogenic effect at ng level on T lymphocyte proliferation in soluble or immobilized conditions and has an immunosuppressive effect at high dose. Conversely, the clone HIT3b has a strong mitogenic effect on T lymphocytes proliferation only under immobilized condition. NK cells also e, Xenopus/Amphibian,press the CD3 antigen in the cytoplasm,Mouse,aking the CD3 (HIT3a) antibody a helpful tool for analyzing the development relationship and the common precursor of both T cells and NK cells.

Catalogue number:	251046
Reactivities:	Human
Applications:	Flow Cytometry
Size:	2 ml
Accession:	P07766
Format:	Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody,PorcineE-conjugated Antibody
Isotype:	mouse IgG2a
Clonality:	HIT3a
Additional info:	T-cell surface glycoprotein CD3; T-cell surface antigen T3/Leu-4; CD3; T3