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CD30 (CD30L Receptor, D1S166E, Ki-1 Antigen, Lymphocyte Activation Antigen CD30, Tumor Necrosis Factor Receptor Superfamily Member 8, TNFRSF8)

CD30 (CD30L Receptor, D1S166E, Ki-1 Antigen, Lymphocyte Activation Antigen CD30, Tumor Necrosis Factor Receptor Superfamily Member 8, TNFRSF8)

Cat no: C2382-13C

Supplier: United States Biological
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CD30 seems to act as a cytokine ligand receptor. It is expressed on normal and neoplastic cells including multinucleated Reed-Sternberg cells, mononuclear Hodgkin cells, most anaplastic large cell lymphomas, and other lymphomas. This antibody will help detect CD30 expression in a variety of tissues. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 1:20-1:40 for 1 hr. at RT Optimal dilutions to be determined by the researcher. Positive Control: Large cell anaplastic lymphoma (membrane staining, some cytoplasmic staining in some cases) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2382-13C
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 1ml
Form: Supplied as a liquid in 15mM sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Supernatant
References: 1. Froese P, Lemke H, Gerdes J, et al.. Biochemical characterization and biosynthesis of the Ki-1 antigen in Hodgkin-derived and virus-transformed human B and T lymphoid cell lines. The Journal of Immunology. 139(6):2081-2087 (1987). 2.Kadin ME, Sako D, Berliner N, et al.. Childhood Ki-1 lymphoma presenting with skin lesions and peripheral lymphadenopathy. Blood, 68(5):1042- 1049 (1986). 3.Stein H, Gerdes J, Schwab U, et al.. Identification of Hodgkin and Sternberg-Reed cells as a unique cell type derived from a newly-detected small-cell population. Int. J. Cancer, 30:445-459 (1982).
Additional info: Recognizes CD30. Species Crossreactivity: Human.

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