CD31 (2F7B) Antibody

Cat no: 252704

Supplier: ABBIOTEC

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Description
Additional Information

CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is e, Xenopus/Amphibian,pressed on the surface of circulating platelets,Mouse,onocytes, neutrophils and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular e, Xenopus/Amphibian,pression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g. immunoglobulins, T-cell receptors, and MHC molecules. In addition, a subgroup comprising 30 members characterized by the presence of one or more immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within their cytoplasmic domain has also been recognized. CD31 has 6 ITIMs within its cytoplasmic domain, is a member of this subfamily.

Catalogue number:	252704
Reactivities:	Human
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	P16284
Antigen:	Purified recombinant fragment of human CD31 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	2F7B2
Additional info:	CD31; Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; CPIIA'; CD31 antigen; PECAM1