CD31 Antibody

Cat no: 250590

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is e, Xenopus/Amphibian,pressed on the surface of circulating platelets,Mouse,onocytes, neutrophils, and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular e, Xenopus/Amphibian,pression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g. immunoglobulins, T-cell receptors, and MHC molecules. In addition, a subgroup comprising 30 members characterized by the presence of one or more immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within their cytoplasmic domain has also been recognized. CD31, which has 6 ITIMs within its cytoplasmic domain, is a member of this subfamily.

Catalogue number:	250590
Reactivities:	Human, Mouse, Bovine, Porcine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P16284
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PECAM1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; CPIIA'; CD31 antigen; PECAM1