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CD31 (CD31 Antigen, EndoCAM, FLJ58394, GPIIA, Platelet Endothelial Cell Adhesion Molecule, PECA1, Pecam 1, Pecam1, Pecam-1)

CD31 (CD31 Antigen, EndoCAM, FLJ58394, GPIIA, Platelet Endothelial Cell Adhesion Molecule, PECA1, Pecam 1, Pecam1, Pecam-1)

Cat no: C2383-03L

Supplier: United States Biological
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CD31 (PECAM-1, Platelet gpIIa Molecule), a ~130kD integral membrane glycoprotein, is expressed in platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney, skin biopsies from conditions such as sarcoidosis and lepromatous leprosy and bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 mediates cell-cell adhesion. Valuable iin the study of benign and malignanat vaascular tumors. Stainiing for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence. Applications: Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2383-03L
Reactivities: Human
Hosts: Mouse
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 1ml
Form: Supplied as a lyophilized powder in PBS, sodium azide. Reconstitute with 1ml ddH2O.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by ammonium sulfate precipitation and DEAE chromatography.
Alternative names: Platelet/endothelial Cell Adhesion Molecule
References: 1. Mazurov, A., et al., 1991, Thromb. Haemost. 66, 494-499.
Additional info: Recognizes human CD31 platelets, monocytes/macrophages, granulocytes and B-cells at ~140kD.

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