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CD31 (CD31 Antigen, EndoCAM, GPIIA, Platelet Endothelial Cell Adhesion Molecule, Pecam 1, Pecam1, Pecam-1) (Biotin)

CD31 (CD31 Antigen, EndoCAM, GPIIA, Platelet Endothelial Cell Adhesion Molecule, Pecam 1, Pecam1, Pecam-1) (Biotin)

Cat no: C2383-03E4

Supplier: United States Biological
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CD31 (PECAM-1, Platelet gpIIa Molecule), a ~130kD integral membrane glycoprotein, is expressed in platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney, skin biopsies from conditions such as sarcoidosis and lepromatous leprosy and bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 mediates cell-cell adhesion. Valuable iin the study of benign and malignanat vaascular tumors. Stainiing for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: Neat-1:200. Use 10ul to label 10e6 cells or 100ul whole blood. Optimal dilutions to be determined by the researcher. Recommended Negative Control: I1904-78R2: IgG1 Murine Negative Control (Biotin) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2383-03E4
Reactivities: Human, Porcine
Hosts: Mouse
Applications: Flow Cytometry
Conjugates: Biotin
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with Biotin.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes porcine CD31, a 140kD cell surface protein, expressed by various cell types, but particularly by endothelial cells. Stimulates tyrosine phosphorylation of CD31 on endothelial cells. Species Crossreactivity: human

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