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CD31 (CD31 Antigen, EndoCAM, GPIIA, Platelet Endothelial Cell Adhesion Molecule, Pecam 1, Pecam1, Pecam-1) (FITC)

CD31 (CD31 Antigen, EndoCAM, GPIIA, Platelet Endothelial Cell Adhesion Molecule, Pecam 1, Pecam1, Pecam-1) (FITC)

Cat no: C2383-03G4

Supplier: United States Biological
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PECAM-1 (CD31), is a type 1 transmembrane protein expressed primarily on endothelial cells, platelets and leukocytes. Has been shown to partially block the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Catalogue number: C2383-03G4
Reactivities: Rat
Hosts: Mouse
Applications: Flow Cytometry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
References: 1. Flaris, N.A. et al. (1993) Characterisation of microglia and macrophages in the central nervous system of the rat. GLIA 7: 34-40. 2. Male, D. et al. (1995) An interferon inducible molecule on brain endothelium which controls lymphocyte adhesion mediated by integrins. Immunology 84: 453-460. 3. Williams, K.C. et al. (1996) PECAM-1 (CD31) expression in the central nervous system and its role in experimental allergic encephalomyelitis in the rat. J. Neurosci. Res. 45(6):747-57.
Additional info: Recognizes rat PECAM-1 (CD31). Has been shown to partially block the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen. Does not react with human.

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