CD31 (PECAM-1, Platelet gpIIa Molecule)

Cat no: C2383-04E

Supplier: United States Biological

0 reviews | Write a Review Pencil

Read More on Supplier Website

Description
Additional Information

Platelet endothelial cell adhesion molecule-1 (CD31/PECAM-1) is a cell-cell adhesion molecule that is expressed on circulating platelets, on leukocytes, and at the intercellular junctions of vascular endothelial cells, where it mediates the interactions of these cells during the process of transendothelial cell migration, thrombosis, wound healing, and angiogenesis (1, 2). CD31/PECAM-1 is an important target glycoprotein in drug-induced immune thrombocytopenia (DITP), a serious complication of drug treatment (3). CD31/PECAM-1 is the physiological ligand for CD38, where expression in a high percentage of malignant cells is a risk factor for patients with B-cell chronic lymphocytic leukemia (B-CLL) (4). Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:5,000

Catalogue number:	C2383-04E
Reactivities:	Human
Hosts:	Rabbit
Applications:	Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size:	100ul
Form:	Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
P type:	Mab
Isotype:	IgG
Purity:	Supernatant
References:	1. Albelda SM, et al. J Cell Biol. 114(5):1059-68, 1991. 2. Kirschbaum NE, et al. Blood. 84(12):4028-37, 1994. 3. Kroll H, et al. Blood. 96(4):1409-14, 2000. 4. Mainou-Fowler T, et al. Int J Oncol. 33(1):169-74, 2008.
Additional info:	Recognizes human CD31.

See Full Product Listings >

CD31 (PECAM-1, Platelet gpIIa Molecule)

Cat no: C2383-04E

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from United States Biological




By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*