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CD31 (PECAM-1, Platelet gpIIa Molecule, Endothelial Cell Marker)

CD31 (PECAM-1, Platelet gpIIa Molecule, Endothelial Cell Marker)

Cat no: C2383-04A

Supplier: United States Biological
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CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Endothelial cells also express this marker, therefore, antibodies to CD31 have been used as a tool to identify the vascular origin of neoplasms. CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of non-vascular tumors (excluding hematopoietic neoplasms) has not been observed. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin, frozen): 1:25-1:50 Optimal dilutions to be determined by the researcher. Positive Control: Appendix, Placenta, Tonsil Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2383-04A
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunohistochemistry
Size: 1ml
Form: Supplied as a liquid in PBS, pH7.4, protein base, sodium azide.
P type: Mab
Purity: Supernatant
References: 1. Parums, DV, et al., J Clin Path 1990;43:752-757 2. De Young, BR, et al., Ap Immuno 1993;1:97-100 3. Alles, JU, et al., J Histo Cyto 1986;34:209-214 4. Santeusanio G, et al. Appl Immunohistochem Mol Morphol. 2003 Dec;11(4):359-63 5. Alexander-Sefre F et al. J Clin Pathol. 2003 Oct;56(10):786-8 6. Allison KH et al. Am J Surg Pathol. 2004 Mar;28(3):298-307.
Additional info: Recognizes human CD31. Staining pattern: Membranous.

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