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CD32 (Fcg Receptor II) (FITC)

Cat no: C2384-01G2


Supplier: United States Biological
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The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul labels of a neat-1:10 working dilution to 10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Catalogue number: C2384-01G2
Reactivities: Human, Canine, Non-Human Primate
Hosts: Mouse
Applications: Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in 0.09% sodium azide, 1% BSA. Labeled with FITC.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: CD32 antigen, CD32A, CD32B, CDw32, Fc fragment of IgG low affinity II receptor for (CD32), Fc fragment of IgG low affinity IIa receptor, Fc fragment of IgG low affinity IIa receptor for (CD32), Fc fragment of IgG low affinity IIb receptor, Fc fragment of IgG low affinity IIb receptor for (CD32), Fc fragment of IgG low affinity IIc receptor, Fc fragment of IgG low affinity IIc receptor for (CD32), Fc gamma receptor IIB, Fc gamma RII a, Fc gamma RII b, Fc gamma RII c, Fc gamma RIIa, Fc gamma RIIb, Fc gamma RIIc, FCG 2, FCG2, FcgammaRIIC, FCGR 2, FcGR, FCGR2, FCGR2A, FCGR2A1, FCGR2B, FCGR2C, FcRII a, FcRII b, FcRII c, IGFR 2, IGFR2, IgG Fc receptor II a, IgG Fc receptor II b, IgG Fc receptor II c, Low affinity immunoglobulin gamma Fc region receptor II a, Low affinity immunoglobulin gamma Fc region receptor II b, Low affinity immunoglobulin gamma Fc region receptor II c, MGC23887, MGC30032
References: 1. Greenman, J. et al. (1991). Characterisation of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab')2 derivative for recruitment of cytotoxic effectors. Mol. Immunol. 28:1243-1254. 2. Can den Herik-Oudjik, I.E. et al. (1994). Functional analysis of human Fc gamma RII (CD32) isoforms expressed in B lymphocytes. J. Immunol. 152:574-585. 3. Lilliehook, I. et al. (1998). Expression of adhesion and Fc gamma-receptors on canine blood eosinophils and neutophils studied by anti-human monoclonal antibodies. Vet. Immunol. Immunopathol. 61:181-193. 4. Larsson, M. et al. (1997). Human dendritic cells handling of binding, uptake and degradation of free and IgG-immune complexed dinitrophenylated human serum albumin in vitro. Immunology. 90:138-146.
Additional info: Recognizes human CD32 at ~40kD. Species Crossreactivity: canine, monkey.

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