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CD344 (Frizzled-4 Receptor, Fz4, FZD4, FzE4, hFz4, FEVR, EVR1)

CD344 (Frizzled-4 Receptor, Fz4, FZD4, FzE4, hFz4, FEVR, EVR1)

Cat no: C2549-44A

Supplier: United States Biological
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There is evidence that CD344 may play a role in retinal angiogenesis, since defects in CD344 are responsible for the familial retinal disease known as exudative vitreoretinopathy 1 (FEVR), and also the cause of the retinal neovascularization disease, Criswick-Schepens syndrome. CD344 has been shown to be a marker for neuronal stem cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16000 Western Blot :0.3-1ug/ml Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: Rabbit Anti Goat IgG (Fc) FITC, HRP Recommended Useful Reagents: HUMAN ILEUM TOTAL PROTEIN LYSATE HUMAN COLON TOTAL PROTEIN LYSATE Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2549-44A
Reactivities: Human, Rat
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% Sodium Azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human CD344, otherwise known as Frizzled-4 in human colon and ileum cell lysates at ~60kD. Species crossreactivity: Rat.

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