Home  >  Products  >  CD36 (Platelet Glycoprotein IV, Synonyms GPIV, Glycoprotein IIIb, GPIIIB, Leukocyte Differentiation Antigen CD36, CD36 Antigen, PAS IV, PAS-4 Protein, Platelet Collagen Receptor)
CD36 (Platelet Glycoprotein IV, Synonyms GPIV, Glycoprotein IIIb, GPIIIB, Leukocyte Differentiation Antigen CD36, CD36 Antigen, PAS IV, PAS-4 Protein, Platelet Collagen Receptor)

CD36 (Platelet Glycoprotein IV, Synonyms GPIV, Glycoprotein IIIb, GPIIIB, Leukocyte Differentiation Antigen CD36, CD36 Antigen, PAS IV, PAS-4 Protein, Platelet Collagen Receptor)

Cat no: C2388-01L

Supplier: United States Biological
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CD36 is a cell surface class B scavenger receptor. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signalling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cyto adherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Applications: Suitable for use in ELISA, Immunofluorescence, Flow Cytometry, Immunoprecipitation, Immunohistochemistry and Functional assays. Other applications not tested. Recommended Dilutions: Flow Cytometry: 2ug labels 10e5 cells Immunoprecipitation: 10ug antibody/ 200ug protein Immunohistochemistry: Frozen sections ELISA: 10ug/ml Functional assays: >1ug/ml Blocks collagen/thrombospondin binding. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2388-01L
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Size: 50ug
Form: Supplied as a liquid in PBS, 0.1% BSA.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: Platelet glycoprotein IV, GPIV, Glycoprotein IIIb, GPIIIB, Leukocyte differentiation antigen CD36, CD36 antigen, PAS IV, PAS-4 protein, Platelet collagen receptor
References: 1. Thibert V et al. Quantitation of platelet glycoprotein IV (CD36) in healthy subjects and in patients with essential thrombocythemia using an immunocapture assay. Thromb Haemost 68:600-5 (1992). 2. Kieffer N et al. Developmentally regulated expression of a 78 kDa erythroblast membrane glycoprotein immunologically related to the platelet thrombospondin receptor. Biochem J 262:835-42 (1989). 3. Edelman P et al. A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors. Blood 67:56-63 (1986).
Additional info: Recognizes CD36 at ~88kD. Species Crossreactivity: human

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