CD3G, Recombinant, Human, aa23-116, His-Tag (CD3-GAMMA, T3G)

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, - delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal- transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. \n\nSource: \nRecombinant protein corresponding to human CD3G, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~13.1kD (117aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATIS\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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