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CD4 (T-cell Surface Glycoprotein CD4, T-cell Surface Antigen T4/Leu-3)

CD4 (T-cell Surface Glycoprotein CD4, T-cell Surface Antigen T4/Leu-3)

Cat no: C2255-07C

Supplier: United States Biological
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CD4 is an immunoglobulin superfamily protein and an accessory protein for MHC class-II antigen/ T-cell receptor interaction. It may regulate T-cell activation. It plays a more general role in mediating cell recognition events than merely those of cellular immune response. The T4 molecule serves as a receptor for the human immunodeficiency virus. A Type I membrane protein, it is expressed on T lymphocytes, B-cells, macrophages, and granulocytes. It is also expressed in a developmentally regulated manner in specific regions of the brain. Applications: Suitable for use in Flow Cytometry, Neutralization and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 0.1-0.25ug/2x10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2255-07C
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by Protein G affinity chromatography.
References: 1. Knapp, W., B. Dorken, et al. eds. (1989). Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.
Additional info: Recognizes human CD4.

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