Home  >  Products  >  CD40 (CDw40, B-cell Surface Antigen CD40, Bp50, CD40L Receptor, MGC9013, p50, Tumor Necrosis Factor Receptor Superfamily Member 5, TNF Receptor Superfamily Member 5, TNFRSF5)
CD40 (CDw40, B-cell Surface Antigen CD40, Bp50, CD40L Receptor, MGC9013, p50, Tumor Necrosis Factor Receptor Superfamily Member 5, TNF Receptor Superfamily Member 5, TNFRSF5)

CD40 (CDw40, B-cell Surface Antigen CD40, Bp50, CD40L Receptor, MGC9013, p50, Tumor Necrosis Factor Receptor Superfamily Member 5, TNF Receptor Superfamily Member 5, TNFRSF5)

Cat no: C2392-03L

Supplier: United States Biological
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CD40 is a glycoprotein important for T-B lymphocytes interactions. The ligand for CD40 is CD154 (CD40L). The function of CD40 is involved in growth, differentiation, and isotype-switching on B cells and also involved to rescue B cells from apoptosis. CD40 is a 48 KD type I single chain trans- membrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin's and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: frozen Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 1ml ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2392-03L
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 1ml
Form: Supplied as a lyophilized powder in 0.1% sodium azide. Reconstitute with 1ml ddH2O.
P type: Mab
Isotype: IgM
Purity: Purified by ammonium sulphate precipitation.
Alternative names: CD40 Antigen, CD40 Molecule
Additional info: Recognizes CD40 at ~50kD. In tissue sections it reacts with B-lymphocytes and with interdigitating reticulum cells.

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