Home  >  Products  >  CD40 (CDw40, B-cell Surface Antigen CD40, Bp50, CD40L Receptor, MGC9013, p50, Tumor Necrosis Factor Receptor Superfamily Member 5, TNF Receptor Superfamily Member 5, TNFRSF5)
CD40 (CDw40, B-cell Surface Antigen CD40, Bp50, CD40L Receptor, MGC9013, p50, Tumor Necrosis Factor Receptor Superfamily Member 5, TNF Receptor Superfamily Member 5, TNFRSF5)

CD40 (CDw40, B-cell Surface Antigen CD40, Bp50, CD40L Receptor, MGC9013, p50, Tumor Necrosis Factor Receptor Superfamily Member 5, TNF Receptor Superfamily Member 5, TNFRSF5)

Cat no: C2392-03M

Supplier: United States Biological
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The human CD40 cell surface antigen is a 48kD glycoprotein expressed by B lymphocytes and weakly by some monocytes. CD40 is involved in the process of B cell selection in germinal centres, and is vital in T cell-B cell interactions. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 20ug/ml Immunohistochemistry (Frozen, paraffin): 1-10ug/ml Requires protein digestion pre-treatment of paraffin embedded sections prior to staining (eg. pronosa or trypsin). Optimal dilutions to be determined by the researcher. IHC Positive Control: Human Tonsil Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2392-03M
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 200ug
Form: Supplied as a liquid in TRIS buffered saline, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified
Alternative names: CD40 Antigen, CD40 Molecule
References: 1. Quadbeck, B. et al. (2002) Maturation of thyroidal dendritic cells in Graves Disease. Scand. J. Immunol. 55: 612 - 620. 2. Kirsch, B. M. et al. (2005) The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function. Arthritis Res. Ther. 7: R694-R703.
Additional info: Recognises human CD40.

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