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Products CD41 (CD41 Antigen, CD41b, gp2b, GPalphaIIb, GPIIb, Gta, HPA3, HPA-3, Integrin alpha IIb, Integrin alpha 2b, ITGA2B, ITGAB, Platelet Glycoprotein IIb of IIb/IIIa Complex, Platelet Membrane Glycoprotein IIb, Platelet Specific Antigen Bak)
| Catalogue number: | C2394-02M |
| Reactivities: | Human |
| Hosts: | Mouse |
| Applications: | Flow Cytometry, Immunofluorescence |
| Size: | 1ml |
| Form: | Supplied as a liquid in 20mM TRIS, 150mM sodium chloride, pH 8.0, 10mg BSA, 0.001% Merthiolate. |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Purified by ammonium sulfate precipitation and Ion Exchange chromatography. |
| Alternative names: | Antigen CD41, Integrin alpha-IIb, Integrin alpha 2b (Platelet Glycoprotein IIb of IIb/IIIa Complex Antigen CD41), Platelet Fibrinogen Receptor alpha |
| References: | 1.Modderman, P.W., et al., 1988, Thrombosis and Haemostasis 60, 68. |
| Additional info: | Recognizes human CD41. Recognizes the intact platelet GPIIb/IIIa complex and human trombocytes and megakaryocytes. Does not bind to dissociated GPIIb, GPIIIa or platelets from patients with Glanzmann thrombasthenia. Does not recognize the vitronectin receptor, which contains GPIIa as a beta subunit (cf. CD61). Activates human thrombocytes and induces thrombocyte aggregation in the absence of trombocyte inhibitors such as EDTA. |
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