CD41 (HIP11) Antibody

Cat no: 250965

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

The CD41 (HIP11) antibody recognizes a 140-kDa glycoprotein which is the ? subunit of the CD41/CD61 (GPIIb/IIIa, ?IIb(B)3) comple, Xenopus/Amphibian, called glycoprotein IIb (GPIIb). GPIIb is a calcium-dependent, no covalently associated heterodimer and contains a heavy chain (GPIIb?) and a light chain (GPIIb(B)) linked by a single disulfide bond. The CD41 antigen is strictly e, Xenopus/Amphibian,pressed on platelets and platelet precursors (megakaryocytes). The CD41/CD61 comple, Xenopus/Amphibian, is the receptor for fibrinogen, fibronectin and von Willebrand factor, and plays a central role in platelet activation and aggregation. The GPIIb/IIIa may be absent or strongly reduced in Glanzmann

Catalogue number:	250965
Reactivities:	Human
Applications:	Flow Cytometry, Immunohistochemistry
Size:	0.1 mg
Accession:	P08514, NP_000410
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG1
Clonality:	HIP11
Additional info:	Integrin alpha-IIb; Platelet membrane glycoprotein IIb; GPalpha IIb; GPIIb; CD41 antigen; ITGA2B; GP2B; ITGAB