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CD42b (HIP1) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 250966

CD42b (HIP1) Antibody

The CD42b (HIP1) antibody recognizes a heterodimer glycoprotein (GPIb?) that contains an ? chain (CD42Bovine, 145 kDa) and a (B) chain (CD42c, 22 kDa) linked by a disulfide bond forming a noncovalent comple, Xenopus/Amphibian, with CD42a (GPI, Xenopus/Amphibian,) and d. CD42b antigen is e, Xenopus/Amphibian,pressed on platelets and megakaryocytes. The GPIb/I, Xenopus/Amphibian, comple, Xenopus/Amphibian, (CD42a-d) serves as a receptor for von Willebrand Factor (vWF) and thrombin, and mediates adhesion of platelets to subendothelium of damaged vascular walls. The absence of the CD42 comple, Xenopus/Amphibian, leads to the Bernard-Soulier Syndrome (BSS). The CD42b (HIP1) antibody inhibits the ristocetin-dependent binding of vWF to platelets, ristocetin-induced platelet agglutination, and partially inhibits collagen-induced aggregation.

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SPECIFICATIONS

Catalog Number

250966

Size

0.1 mg

Applications

FC, IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Isotype

mouse IgG1

Accession

P07359

Clonality

HIP1

Additional Info

CD42b; Platelet glycoprotein Ib alpha chain; Glycoprotein Ibalpha; GP-Ib alpha; GPIb-alpha; GPIbA; Antigen CD42b-alpha; Glycocalicin

SUPPLIER INFO

ABBIOTEC

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