CD42b (HIP1) Antibody

Cat no: 251022

Supplier: ABBIOTEC

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Description
Additional Information

The CD42b (HIP1) antibody recognizes a heterodimer glycoprotein (GPIb?) that contains an ? chain (CD42Bovine, 145 kDa) and a (B) chain (CD42c, 22 kDa) linked by a disulfide bond forming a noncovalent comple, Xenopus/Amphibian, with CD42a (GPI, Xenopus/Amphibian,) and d. CD42b antigen is e, Xenopus/Amphibian,pressed on platelets and megakaryocytes. The GPIb/I, Xenopus/Amphibian, comple, Xenopus/Amphibian, (CD42a-d) serves as a receptor for von Willebrand Factor (vWF) and thrombin, and mediates adhesion of platelets to subendothelium of damaged vascular walls. The absence of the CD42 comple, Xenopus/Amphibian, leads to the Bernard-Soulier Syndrome (BSS). The CD42b (HIP1) antibody inhibits the ristocetin-dependent binding of vWF to platelets, ristocetin-induced platelet agglutination, and partially inhibits collagen-induced aggregation.

Catalogue number:	251022
Reactivities:	Human
Applications:	Flow Cytometry
Size:	2 ml
Accession:	P07359
Format:	Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody, FITC-conjugated Antibody
Isotype:	mouse IgG1
Clonality:	HIP1
Additional info:	CD42b; Platelet glycoprotein Ib alpha chain; Glycoprotein Ibalpha; GP-Ib alpha; GPIb-alpha; GPIbA; Antigen CD42b-alpha; Glycocalicin