Home  >  Products  >  CD43 (CD43 Antigen, Galactoglycoprotein, GALGP, GPL115, Leukocyte Sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN)
CD43 (CD43 Antigen, Galactoglycoprotein, GALGP, GPL115, Leukocyte Sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN)

CD43 (CD43 Antigen, Galactoglycoprotein, GALGP, GPL115, Leukocyte Sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN)

Cat no: C2397-76V

Supplier: United States Biological
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CD43 is a nonlineage antigen that is expressed on several cell types such as T-lymphocytes, granulocytes and monocytes. The CD43-antibody induces apoptosis of lineage marker-negative bone marrow hematopoietic progenitor cells that express CD34 at a high density (CD34hi LIN-). However stem cells, more primative cells and differentiated myeliod and mature lymphocytes do not respond to CD43 mediated stimulation by apoptosis. Therefore it appears to be a narrow window within the differentiation pathway of stem cells towards mature hematopoietic cells that seems sensitive to apoptosis triggered by CD43. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: Non-reducing conditions Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2397-76V
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
Alternative names: Human Gene for Sialophorin, Leucocyte Sialoglycoprotein
References: 1. Stefanov
Additional info: Recognizes human CD43. Reacts with the neuraminidase sensitive epitope of the CD43 molecule, which is involved in lymphocyte activation.

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