Home  >  Products  >  CD45 (Receptor-type Tyrosine-protein Phosphatase C, Leukocyte Common Antigen, L-CA, Lymphocyte Antigen 5, Ly-5, T200, Ptprc, Ly-5, Protein Tyrosine Phosphatase, Receptor Type, C, B220, Lyt-4)
CD45 (Receptor-type Tyrosine-protein Phosphatase C, Leukocyte Common Antigen, L-CA, Lymphocyte Antigen 5, Ly-5, T200, Ptprc, Ly-5, Protein Tyrosine Phosphatase, Receptor Type, C, B220, Lyt-4)

CD45 (Receptor-type Tyrosine-protein Phosphatase C, Leukocyte Common Antigen, L-CA, Lymphocyte Antigen 5, Ly-5, T200, Ptprc, Ly-5, Protein Tyrosine Phosphatase, Receptor Type, C, B220, Lyt-4)

Cat no: C2400-20Q

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
CD45 is a 180-240kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)0.25ug/10e6 cells in 100ul volume Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2400-20Q
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85. 3. Kishihara K, et al. 1993. Cell 74:143. 4. Pulido R, et al. 1988. J. Immunol. 140:3851.
Additional info: Recognizes mouse CD45.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave