CD45RA (FITC), CD4 (PE), Dual Color

Leukocyte common antigen is expressed exclusively on the surface of hematolymphoid cells and their progenitors, including T and B lymphocytes, granulocytes, monocytes, and macrophages. Mature erythrocytes and megakaryocytes do not express CD45. The CD45 antibody is an important component of the antibody panel used to distinguish hematolymphoid neoplasms from non-hematolymphoid neoplasms, including undifferentiated or anaplastic large cell tumors (malignant lymphoma, melanoma, and carcinoma). In a study of nasophryngeal biopsies, LCA staining was positive for all malignant melanomas and negative for all nasopharyngeal carcinomas. LCA may be used together with cytokeratin antibodies to identify the cell-lineage of anaplastic tumors, demonstrating the ability to identify lymphoma and carcinoma in up to 88% of cases in a single study. Consists of a mixture of three monoclonal antibodies: CD45, CD45RA and CD45RB.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution: \nFlow Cytometry: Reagent is tested for flow cytometric analysis using 100ul peripheral blood cells or 20ul/10e6 cells.\n\nStorage and Stability: \nStorage at 4 degrees C, should not be frozen and avoid prolonged exposure to light.

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SPECIFICATIONS

Catalog Number

C2400-44J

Size

50Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Dual color combination consisting of FITC conjugated and R-PE conjugated monoclonal antibodies mixed in optimal ratio.

P Type

Mab

Isotype

IgG2a+IgG2b

Additional Info

CD45RA, CD4