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Products CD45RC (CD45 Antigen, B220, GP180, Leukocyte Common Antigen, LCA, L-CA, LY5, LY-5, Protein Tyrosine Phosphatase Receptor Type C Polypeptide, PTPRC, T200, T200 Glycoprotein)
| Catalogue number: | C2400-61R |
| Reactivities: | Rat |
| Hosts: | Mouse |
| Applications: | Flow Cytometry, Immunohistochemistry |
| Size: | 500ug |
| Form: | Supplied as a liquid in PBS, pH 7.4. No preservatives added. |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Purified by Protein G affinity chromatography. |
| References: | 1. Spickett, G.P. et al. (1983) MRC OX-22, a monoclonal antibody that labels a new subset of T lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen. J. Exp. Med. 158:795-810.2. Arthur, R.P. and Mason, D.W. (1986) T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation. J. Exp. Med. 163:774-786.3. Pelegri, C et al. (2001) Prevention of adjuvant arthritis by the W3/25 anti-CD4 monoclonal antibody is associated with a decrease of blood CD4+CD45RChigh T cells. Clin. Exp. Immunol. 125:470-477. |
| Additional info: | Recognizes rat CD45RC, the high molecular weight form of the leukocyte common antigen. The antigen is found on B cells, approximately 50% of bone marrow cells, all CD8+ve T cells, but splits CD4+ve T cells into two populations, CD4+CD45RChigh (Th1-like) and CD4+CD45RClow (Th2-like). |
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