Home  >  Products  >  CD49f (CD49 Antigen-like Family Member F, CD49f Antigen, Integrin alpha 6, Integrin alpha-6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6)
CD49f (CD49 Antigen-like Family Member F, CD49f Antigen, Integrin alpha 6, Integrin alpha-6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6)

CD49f (CD49 Antigen-like Family Member F, CD49f Antigen, Integrin alpha 6, Integrin alpha-6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6)

Cat no: C2405-03H

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
The CD49f antigen, molecular weight 30/31, 120kD (GP Ic or VLA-6 alpha-chain), can form distinct complexes with either the CD29 antigen (GP IIa or VLA beta chain), resulting in the VLA-6 (alpha-6, beta-1) complex which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6, beta-4 complex which is expressed on various human epithelial cells. Platelet VLA-6 functions as a laminin receptor and platelet adhesion to laminin is inhibited by this antibody. Applications: Suitable for use in Indirect Immunofluorescence, Flow Cytometry, Fluorescent Microscopy and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2405-03H
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Size: 1ml
Form: Supplied as a liquid in 20mM TRIS, 150mM sodium chloride, pH 8.0,10mg BSA, 0.001% Merthiolate.
P type: Mab
Isotype: IgG2a
Purity: Purified by Ion Exchange chromatography.
Alternative names: DKFZp686J01244, FLJ18737, Integrin alpha Chain
References: 1. Sonnenberg, A., et al., 1987, J. Biol. Chem. 262, 10376. 2. Hemler, M.E., et al., 1988, J. Biol. Chem. 263, 7660. 3. Sonnenberg, A., et al., 1988, J. Biol. Chem. 263, 14030. 4. Hemler, M.E., et al., 1989, J. Biol. Chem. 264, 6529. 5. Sonnenberg, A., et al., 1988, Nature 336, 487.
Additional info: Recognizes human CD49f. Reacts with platelets, megakaryocytes, T-lymphocytes and common acute lymphoblastic leukemia cells (alpha-6, beta-1).

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave