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CD5 (T-cell Surface Glycoprotein CD5, Lymphocyte Antigen T1/Leu-1, LEU1)

CD5 (T-cell Surface Glycoprotein CD5, Lymphocyte Antigen T1/Leu-1, LEU1)

Cat no: C2256-25L

Supplier: United States Biological
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CD5 is a 67kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72. Applications: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: (same/less than)1ug/10e6 cells in 100ul Immunohistochemistry: acetone-fixed frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2256-25L
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Knapp, W., et al. 1989. Leucocyte Typing IV, Oxford University Press. New York. 2. Renaudineau, Y., et al. 2005. Blood 106:2781. (WB, IHC) 3. Porter, J.C. and Hogg, N., 1997. J. Cell Biol. 138:1437. 4. Saliba, A.E., et al. 2010. P. Natl. Acad. Sci. USA 107:14524. 5. Kap, Y., et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC) 6. Kipps, T. 1988. Adv. Immunol. 47:117. 7. Resnick, D., et al. 1993. Trends Biochem. Sci. 19:5. 8. Wood, G.S., et al. 1992. Am. J. Pathol. 14:789.
Additional info: Recognizes human CD5. Species Crossreactivity: chimpanzee.

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