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CD50 (Intercellular Adhesion Molecule 3, ICAM-3, CDw50, ICAM-R, ICAM3)

CD50 (Intercellular Adhesion Molecule 3, ICAM-3, CDw50, ICAM-R, ICAM3)

Cat no: C2405-06H

Supplier: United States Biological
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CD50 is a 120-140 kD type I membrane protein also known as intercellular adhesion molecule 3 (ICAM-3). It is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. CD50 is a member of the Ig superfamily. It provides costimulatory signal for T cells and regulates cell adhesion through interaction with LFA-1 (CD11a/CD18, aL/ b2) integrin. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2405-06H
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by immunoaffinity chromatography.
References: 1. deFougerolles, AR. and TA. Springer, et al, 1992. J. Exp. Med. 175:185. 2. Valent, P., et al. 2001. Immunol. Rev. 179:74.
Additional info: Recognizes human CD50.

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