Home  >  Products  >  CD51 (CD51 Antigen, Integrin alpha V, Integrin alpha-V, ITGAV, Msk8, Vitronectin Receptor alpha Polypeptide, Vitronectin Receptor Subunit alpha, VNRA)
CD51 (CD51 Antigen, Integrin alpha V, Integrin alpha-V, ITGAV, Msk8, Vitronectin Receptor alpha Polypeptide, Vitronectin Receptor Subunit alpha, VNRA)

CD51 (CD51 Antigen, Integrin alpha V, Integrin alpha-V, ITGAV, Msk8, Vitronectin Receptor alpha Polypeptide, Vitronectin Receptor Subunit alpha, VNRA)

Cat no: C2405-11T

Supplier: United States Biological
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The CD51 antigen, alpha chain of vitronectin receptor (VNR-alpha chain) forms a complex with: the CD61 antigen (GP IIIa or Beta-3 chain) resulting in the alpha- beta-3 complex, which is expressed on human platelets; the beta-5 integrin, resulting in the alpha-beta-5 complex, which is expressed on human monocytes and marcophages; the beta-1 integrin, resulting in the alpha-beta-1 complex. The platelet alpha-beta-3 complex functions as a vitronectin receptor and platelet adhesion to vitronectin is inhibited by this monoclonal antibody. Applications: Suitable for use in Indirect Immunofluorescence, Flow Cytometry, Fluorescent Microscopy and Functional studies on vitronectin receptor on human platelets . Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2405-11T
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence
Size: 1ml
Form: Supplied as a liquid in 20mM TRIS, 150mM sodium chloride, pH 8, 10mg BSA, 0.001% Mertiolate.
P type: Mab
Isotype: IgG1
Purity: Purified by Ion Exchange chromatography.
Alternative names: DKFZp686A08142, Integrin alpha-V Heavy Chain, Integrin alpha-V Light Chain
References: 1. Vries, J.E., et al., 1986, Int. J. Cancer 38, 465.
Additional info: Recognizes human CD51.

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