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CD51 (Integrin alpha V, Vitronectin alpha Subunit Receptor, VNR)

CD51 (Integrin alpha V, Vitronectin alpha Subunit Receptor, VNR)

Cat no: C2405-13G

Supplier: United States Biological
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Cellular Localization: Cell Membrane Positive Control: Positive control: Tonsil. 125/124kD (reduced), 150kDa (non-reduced). Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry (Fr). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2405-13G
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: ITGAV, Vitronectin receptor alpha polypeptide, Vitronectin receptor alpha polypeptide antigen CD51, Vitronectin receptor subunit alpha, VNRA
References: This product has been used in:Marshall JF et al. Alpha v beta 1 is a receptor for vitronectin and fibrinogen, and acts with alpha 5 beta 1 to mediate spreading on fibronectin. J Cell Sci 108 ( Pt 3):1227-38 (1995). Horton MA et al. Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. Cancer Res 45:5663-9 (1985).
Additional info: Reacts with alpha V beta 3. 23C6 may be useful for bone resorption modulation, osteoclast identification, receptor purification, malignant melanoma identification and treatment. Species Crossreactivity: Crossreacts with Human. Not yet tested in other species.

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