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CD54, Mouse IgG2a Fc Fusion Protein (BB2, Intercellular Adhesion Molecule 1, ICAM1, ICAM-1, Major Group Rhinovirus Receptor, P3.58)

Cat no: C2409-14V

CD54, Mouse IgG2a Fc Fusion Protein (BB2, Intercellular Adhesion Molecule 1, ICAM1, ICAM-1, Major Group Rhinovirus Receptor, P3.58)

Human CD54 (ICAM-1) mediates cell adhesion by binding to the integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). CD54 expression on resting peripheral blood leukocytes is weak but is upregulated on activated T and B lymphocytes and on monocytes.\n\nMolecular Structure: A soluble dimeric fusion protein consisting of the extracellular (451aa) domain of human CD54 (including

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SPECIFICATIONS

Catalog Number

C2409-14V

Size

25ug

Applications

ELISA

Form

Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 150mM sodium chloride. No preservative added.

Purity

Purified by size exclusion.

References

1. A.R. Berendt, et al, (1992) Cell 68: 71-81, 2. I. Dransfield, et al, (1992) J Cell Biol 116: 1527-1535, 3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1548-1550, 4. P.L. Reilly, et al, (1995) J Immunol 155: 529-532

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