Home  >  Products  >  CD56 (CD56 Antigen, Cell Adhesion Molecule Neural 1, MSK39, Neural Cell Adhesion Molecule 1, NCAM 1, NCAM1, NCAM 120, NCAM 140, NCAM 180)
CD56 (CD56 Antigen, Cell Adhesion Molecule Neural 1, MSK39, Neural Cell Adhesion Molecule 1, NCAM 1, NCAM1, NCAM 120, NCAM 140, NCAM 180)

CD56 (CD56 Antigen, Cell Adhesion Molecule Neural 1, MSK39, Neural Cell Adhesion Molecule 1, NCAM 1, NCAM1, NCAM 120, NCAM 140, NCAM 180)

Cat no: C2410-61U

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
CD56, a 175-220kD glycoprotein, is a novel member of Ig super family. It is expressed as 3 major isoforms and consists of 5 Ig-like domains and 2 Fibronectin-type III domains in the extracellular region. It is widely expressed in nervous system, on NK cells and a specific set of T-cells. CD56+ NK cells and T-cells are unique in their ability to mediate cell-mediated cytotoxicity against certain tumor cell targets without MHC restriction. Other physiological functions of CD56 include mediating cell adhesion through homophilic and heterophilic interaction and activating intracellular signaling pathways resulting in neutrite extension and fasciculation, cell migration and synapses formation in brain. It is also vital for neuronal development and plasticity in adult brain. It is used as a tumor marker in various cancers such as NK lymphomas and Merkel cell carcinoma. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (formalin fixed paraffin embedded): 1:25-1:75 Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher. Positive Control: Neuroblastoma Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2410-61U
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 500ul
Form: Supplied as a liquid, 0.05% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Gerardy et al. Intl. J Cancer. Supplement 8:38, 1994. 2. Michalides et al. Intl. J Cancer. Supplement 8: 34, 1994 3. Kibbelaar et al. Europ. J Cancer 27:431, 1991. 4. Lanier et.al The Journal of Immunology 146 (12); 4421-4426 (June 15, 1991) 5. Prag et.al Journal of Cell Science 115; 283-292 (2002)
Additional info: Recognizes human CD56.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave