Home  >  Products  >  CD58 (Ag3, CD58 antigen, LFA3, LFA-3, Lymphocyte function-associated antigen 3 precursor, Surface glycoprotein LFA-3)
CD58 (Ag3, CD58 antigen, LFA3, LFA-3, Lymphocyte function-associated antigen 3 precursor, Surface glycoprotein LFA-3)

CD58 (Ag3, CD58 antigen, LFA3, LFA-3, Lymphocyte function-associated antigen 3 precursor, Surface glycoprotein LFA-3)

Cat no: C2413-44C

Supplier: United States Biological
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CD58 antigen has wide distribution over many tissues, both hematopoietic and non-hematopoietic cells, including leukocytes, erythocytes, endothelial cells, epithelial cells and fibroblasts. There are two isoforms of CD58 antigen: a glycosylphosphatidylinositol (GPI)- anchor form and a transmembrane form. Both forms are expressed on the same cell type, and however, erythrocytes only have the GPI-anchored isoform. CD58 is the ligand for CD2, and functions as an adhesion molecule and mediates its signal through CD2, which is expressed on T cells and NK cells. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2413-44C
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
References: van der Merwe, P.A. & Davis, S.J. (2003) Annu. Rev. Immunol. 21,659 ?" 684; Wang, J-H. et. al. (1999) Cell 97,791 ?" 803; Wallner, B.P. et. al. (1987) J. Exp. Med. 166,923 ?" 932.
Additional info: Recognizes human CD58 (also known as LFA-3)

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